ILTs in aortic aneurysm are thus biologically active, facilitating the secretion of various inflammatory cytokines (interferon gamma (IFNγ), IL-1α), platelet-derived factors (PF4), Platelet-derived growth factor (PDGF)), TGFβ, MMPs (MMP8, MMP9) as well as various neutrophil products such as urokinase plasminogen activator (uPA), proteinase-3, cathepsins, myeloperoxidase (MPO) and elastase, within both the aortic wall and lumen. This evidence concerns the gene IFNG and aortic aneurysm.