Certain kidney diseases involve CXCR3 in their development, with glucocorticoids having been shown to diminish CXCR3+ T cell influx during c-ANCA vasculitis and cause increased CXCR3+ T cell numbers in kidney biopsies from p-ANCA vasculitis patients, indicating a poorer prognosis [28]. The gene discussed is CXCR3; the disease is kidney disorder.