Multivariable logistic regression analysis, adjusted for all osteoporosis risk factors (age, female sex, weight, height, DM, HTN, CKD-MBD factors, nutritional markers such as PNI score, T-cholesterol, CRP) (Model 2), with reference values, showed intergroup OR for the occurrence of osteoporosis increased with moderate SMA, OR 7.56; low SMA, OR 8.25; and very low SMA, OR 30.59, all of which were statistically significant. This evidence concerns the gene CRP and chronic kidney disease.