Significant associations have been demonstrated between HLA-DRB1*03 and many autoimmune diseases (AIDs), including Graves’ disease [54,55] and Graves’ orbitopathy [56], Hashimoto’s thyroiditis [57], Addison’s disease [58], myasthenia gravis [59], Guillain–Barré syndrome [60], and systemic lupus erythematosus (SLE) [61]. The gene discussed is HLA-DRB1; the disease is primary adrenal insufficiency.