In October 2022, when she was receiving tocilizumab at a reduced dose (162 mg/2 weeks) during an episode of mild acute leucopenia and neutropenia for two months (total leukocytes 3990× mm3, total neutrophils 1310× mm3, total lymphocytes 1380× mm3, platelets 190,000× mm3, serum creatinine 1.02 mg/dL, glomerular filtration rate 53 mL/min, erythrocyte sedimentation rate (ESR) 7 mm/hour, C-Reactive protein (CRP) 0.3 mg/L), she was admitted to the emergency room with a red left eye, photophobia plus epiphora. This evidence concerns the gene CRP and Photophobia.