In addition, gastric cancers with CDX2 induction and a parallel induction of HNF4A displayed a higher rate of CIN (83% of cases) compared with all cancers with CDX2 induction (CIN in 63.3% of cases, Table 7) or the cohort with no CDX2 induction (CIN in 43.1% of cases). Here, CDX2 is linked to cancer.