These two groups were clinically distinct—the inflammatory group had an increased swollen joint count (5.0), high CRP levels (1.0 mg/dL), and high DAS28-CRP (5.3), while the non-inflammatory group had a higher proportion of obesity (55%) and fibromyalgia (15%) [27]. The gene discussed is CRP; the disease is obesity due to melanocortin 4 receptor deficiency.