Median changes in NT-proBNP in patients with IPAH, PH-HFpEF with PAWP ≤ 15 mmHg, and PH-HFpEF with PAWP > 15 mmHg were −381 [−1226, −5] ng/L, 0 [−438, 295] ng/L, and −11 [−794 to 402] ng/L, respectively (Figure 3C). Here, NPPB is linked to idiopathic pulmonary arterial hypertension.