The participants looked into known strategies to delay CKD progression and improve cardiovascular prognosis, such as lifestyle interventions, blood pressure control, RAAS inhibition, SGLT2 inhibition, and mineralocorticoid receptor antagonists, and reviewed their role for different etiologies of kidney disease such as lupus nephritis, small vessel vasculitis, IgA nephropathy (IgAN), autosomal dominant polycystic kidney disease (ADPKD), Alport syndrome, and kidney amyloidosis. This evidence concerns the gene NR3C2 and chronic kidney disease.