The last of the core subunits, RBBP4/7, can also theoretically be regulated to decrease the activity of PRC2 given its role in both the stabilization of SUZ12 and interactions with histone tails aiding PRC2 recruitment; however, although considerable research regarding the role of RBBP4/7 within cancer has been conducted, there has been a limited focus on targeting the complex with therapeutic intentions [41]. This evidence concerns the gene RBBP4 and cancer.