SOD1 gene overexpression was accompanied by a significant increase in SOD enzymatic activity in the v-COVID-19 (p = 0.007, 1.3-fold increase) and u-COVID-19 (p = 0.002, 1.2-fold increase) subgroups compared to the v-CTRL subgroup (Figure 2D). The gene discussed is SOD1; the disease is COVID-19.