F8 and hemophilia A: MiR-374b-5p and miR-30c-5p, both expressed in the human liver alongside the FVIII protein, were analyzed in two patients with mild and moderate hemophilia A (HA) who showed no mutations in their F8 gene; it was proven that the overexpression of MiR-374b-5p and miR-30c-5p decreased FVIII expression, while an miR-30c inhibitor partially restored FVIII expression [18].