Bleeding score tools, such as a Mariani score or the Di Minno patients’ classification [2,22], are currently used to assess the probability of bleeding in patients with an FVII deficiency, but there is no correlation between the factor VII activity level and bleeding score, despite the fact that the bleeding score is a valuable clinical tool for assessing patients with an elevated bleeding risk [4,24,25]. Here, F7 is linked to hyperinsulinemic hypoglycemia, familial, 4.