In a previous study, GATA3 downregulation was attributed in HCC to the formation of GATA3-antisense (GATA3-AS) that antagonizes GATA3 and functions as a cis-regulatory element, thus directing m6A modification by KIAA1429 on the GATA3 pre-mRNA [46]. This evidence concerns the gene GATA3 and hepatocellular carcinoma.