Bleomycin-induced Cxcl1 production in lungs and Cxcl1 levels correlated with neutrophilic airway inflammation in mice preceding pulmonary fibrosis [23,245,246,247] which were attenuated by the Cxcr2 antagonists [245,246] or endothelial glycosaminoglycans antagonism [23]. The gene discussed is CXCL1; the disease is pulmonary fibrosis.