Mutations in nucleophosmin 1 (NPM1), FMS-like tyrosine kinase 3 (FLT3) and CCAAT/enhancer-binding protein α (CEBPA) contribute to risk stratification of cytogenetically normal acute myeloid leukemia (CN-AML) [1,2,3]. This evidence concerns the gene FLT3 and acute myeloid leukemia.