GPT and steatosis: When hUC MSC EVs were administered weekly (i.v.; 20 mg/kg) to C57BL/6J mice on a 6-week methionine-choline-deficient (MCD) diet, the mice exhibited less body weight reduction, improved AST and ALT, and reduced steatosis and hepatocyte ballooning as compared to control mice on an MCD diet but not receiving EVs [129].