In a similar manner, the study by Polini et al. [27] focused on the tumor suppressor roles of hsa-miR-193a-3p and -5p in melanoma, revealing that their ectopic over-expression in melanoma cell lines substantially reduced cell viability and affected key signaling pathways involved in proliferation and apoptosis, such as Akt and Erk. Here, AKT1 is linked to melanoma.