The analysis of human gastric cancer tissue microarrays shows high levels of dopamine- and cAMP-regulated phosphoprotein Mr 32000 (DARPP-32) and positive immunostaining for nuclear signal transducer and activator of transcription 3 (STAT3) in cancer tissues as compared to non-cancer, histologically normal tissues. The gene discussed is PPP1R1B; the disease is gastric cancer.