Using gene set enrichment analysis and Hallmarks of cancer, we observed that oxidative-phosphorylation, E2F and MYC targets, DNA repair and coagulation pathways were upregulated in high IBP score tumors, while inflammatory response, gamma response, UV response, allograft rejection and mesenchymal transition were upregulated in low IBP score tumors (Figure 5C). This evidence concerns the gene MYC and cancer.