Similarly, curcumin, also known as diferuloylmethane, derived from plants of the Curcuma longa species, and celecoxib, a well-known nonsteroidal anti-inflammatory drug and cyclooxygenase-2 inhibitor, have also exhibited a reliable and selective NF-κB-inhibiting activity against tumor proliferation and progression [174]. This evidence concerns the gene NFKB1 and neoplasm.