NPPB and type 2 diabetes mellitus: Among several biomarkers, the European Society of Cardiology/European Association for the Study of Diabetes (ESC/EASD) have introduced the use of N-terminal pro b-type natriuretic peptide (NT-proBNP) as a surrogate marker for T2DM patients in the prediction of cardiovascular disease (CVD) risk [9,10,11].