Similarly, Kusumoto et al. found that the Laboratory Risk Indicator for Necrotizing Fasciitis score, with a cutoff of 6, and a CRP + neutrophil-to-lymphocyte ratio with a cutoff of 27, were effective for diagnosing severe cases, and their decision tree analysis, using a systemic immune-inflammation index (SII) cutoff of ≥282, achieved a diagnostic accuracy of 89.3%. The gene discussed is CRP; the disease is fasciitis.