Twenty of the variants were reported to be associated with the occurrence of hearing loss, while thirteen of the novel variants were found to segregate in 11/43 HL families, inlcuding DIAPH3 c.2256_2257insT, PTPRQ c.6293T>C, CDH23 c.4859T>A, MPZL2 c.393_436+21del, TCOF1 c.3997_4007del, LOXHD1 c.2438T>A and c.1759C>T, EYA1 c.1350_1353delTAATinsCAGACA, FDXR c.1069G>T and c.364C>T, ATP7B c.4014T>A, SOX10 c.133del, and AIFM1 c.1771-14T>A. This evidence concerns the gene AIFM1 and Hodgkins lymphoma.