Ge et al. [36] were the first to use digital pathology to evaluate steatosis patterns in the mouse liver, describing the digital image obtained through automatic recognition and the recognition area stained with oil red O. De Rudder et al. [37] showed that an automated measurement method for fatty degeneration based on quantification of the area of hepatic bullous steatosis significantly correlated with CT liver density, fat content, steatosis score, and CD36 expression. This evidence concerns the gene CD36 and hepatitis A virus infection.