Heatmap analysis (Supplementary Figures S1–S5) highlighted that five peptides, which are associated with the alpha-crystallin B chain (CRYAB), fused in sarcoma/translocated in liposarcoma (FUS/TLS), cornichon family AMPA receptor auxiliary protein 3 (CNIH3), signal peptidase complex subunit 1 (SPCS1), and one uncharacterized protein, were overlapped between the WS and WS + WB groups (Supplementary Figure S4). This evidence concerns the gene SPCS1 and Tumor Lysis Syndrome.