HCCS and microphthalmia: Individual 9 in Reis et al. (2023) [11] with a ~4.08 Mb deletion including HCCS had a clinical diagnosis of Axenfeld–Rieger syndrome with bilateral congenital glaucoma, polycoria, microphthalmia (right smaller than left), corneal opacity with failed corneal transplant in adulthood, and small congenital cataracts.