Individual 9 in Reis et al. (2023) [11] with a ~4.08 Mb deletion including HCCS had a clinical diagnosis of Axenfeld–Rieger syndrome with bilateral congenital glaucoma, polycoria, microphthalmia (right smaller than left), corneal opacity with failed corneal transplant in adulthood, and small congenital cataracts. The gene discussed is HCCS; the disease is Developmental cataract.