Additionally, Capaci V et al. identified another mechanism by which mutant p53 regulates Golgi-associated proteins in various malignant tumor cells with different p53 mutations (breast cancer MDA-MB-231/p53R280K, SK-BR-3/p53R175H, prostate cancer DU145/p53P223L,V274F, and colorectal cancer HT-29/p53R273H). The gene discussed is TP53; the disease is cancer.