GBA1 and Parkinson disease: A study conducted on individuals primarily from North Africa, mainly Algeria, identified three heterozygous GBA1 mutations (K27R, R131C, N370S/N409S), one homozygous R131C mutation, and two complex alleles [L444P/E326K, RecNciI (A456P/V460V/L444P)] in nine patients with PD (9 of 194, 4.6%), while only one heterozygous D443N variant was found in the control group (1 of 177, 0.5%) [80].