GBA1 and Parkinson disease: In a separate targeted screening of a Brazilian PD cohort, 2.8% of index cases (4 out of 141) tested positive for the most common GBA1 mutations (L444P/L483P or N370S/N409S), three with the L444P/L483P variant (2.1%) and one with the N370S/N409S variant (0.7%) [76].