Differential genes in the si vs. nc group were found to be enriched in signaling pathways such as the NOD-like receptor signaling pathway, the calcium signaling pathway, lipids and atherosclerosis, Wnt signaling pathway, cAMP signaling pathway, AGE-RAGE signaling pathway in diabetic complications, and regulation of lipolysis in adipocytes in the KEGG enrichment results. This evidence concerns the gene RENBP and atherosclerosis.