ALOX12 and cancer: This means that the WT-ALOX12 and FKBP5 antitumor effects derive from the induction of autophagy, and a higher level of somatic mutations accumulated on FKBP5 and ALOX12 genes in cancer patients inhibit ALOX12 and FKBP5 gene expression and increase cancer progression in cancer patients who were exposed to stressful life events.