The results showed that there was a significant correlation between high NRAS-AS expression in liver cancer patients and TNM staging of tumor tissue (p = 0.011), capsule condition (p = 0.013), tumor size (p = 0.008), total bilirubin level (p = 0.003), and AFP level (p = 0.023) (p < 0.01), while there was no correlation with patient’s gender (p = 0.299), age (p = 0.302), and differentiation degree (p = 0.427), and there was no significant statistical difference (p > 0.05). Here, AFP is linked to liver cancer.