The aim of this study was to investigate the association of SAP components, NF-κB, IL-1β, Casp 1, TNF-α and C3 expression with TE-associated neuropathology on day 10 (transition from acute to early chronic phase), day 20 (transition from early/middle chronic phase) and day 30 (chronic phase) post-infection, which is considered to be the transition phase from systemic acute infection to early chronic phase, and to show whether there is a day-dependent correlation between them. Here, TNF is linked to infection.