In vitroGreater uptake of NPs in tumor cellsPotent radiosensitizer—significantly increased γ-H2AX staining (a marker for double-stranded breaks)In vivoSignificantly higher accumulation at tumor site (p < 0.01)Efficacy in accumulating in tumor hypoxic regionsStrong inhibition of glioma growth. Here, H2AX is linked to neoplasm.