A study of methylation analysis of the DPP6, RALYL and GSX1 gene regions in a cohort of women aged ≥30 years attending cervical cancer screening in the Stockholm region of Sweden revealed that early screening for cervical cancer can be effectively performed by detecting the degree of methylation of the three genes in conjunction with HPV16/18 genotyping. The gene discussed is GSX1; the disease is cervical carcinoma.