The methylation of EBNA1, LMP1, R ASSF1A, DAK, ITGA9, P16, WNT7A, CHFR, CYB5R2, WIF1, RIZ1, and FSTL1 genes was found to be significantly different in Moroccan patients with NPC compared to patients with NPC in Southern China. Here, CYB5R2 is linked to nasopharyngeal carcinoma.