The methylation analysis of the genes EBNA1, LMP1, RASSF1A, DAK, ITGA9, P16, WNT7A, CHFR, CYB5R2, WIF1, RIZ1, and FSTL1 [43] in Moroccan and Southern Chinese patients with NPC revealed differences in DNA methylation sensitivity and specificity among NPC populations from these different regions. This evidence concerns the gene CDKN2A and nasopharyngeal carcinoma.