FGF10 and LADD syndrome: Hence, mutations in the Fgf10 gene cause glandular defects (e.g., Lacrimo-auriculo-dento-digital syndrome (LADD) and aplasia of the lacrimal and salivary glands (ALSG)) [121,122,123] and lung defects (e.g., lethal lung developmental disorders [124,125], chronic obstructive pulmonary disease [126], bronchopulmonary dysplasia [118]).