PINK1 and myocardial infarction: In recent research, it was found that the overexpression of miR-147-y in rat cardiomyocytes leads to an improvement in cell damage in rat myocardial infarction models [140]; the study by Gao et al. demonstrated that the cell death caused by DOX was reduced by improving mitophagy, as evidenced by a decrease in P62 levels and an increase in various markers such as LC3, PINK1, Parkin mRNA, LC3II/I, beclin-1, PINK1, and Parkin, including p-parkin (Ser65) protein expression.