Finally, the efficacy of H10 (8, Figure 2), a novel pyrrolo [2,1-c][1,4] benzodiazepine-3,11-dione selective HDAC6 inhibitor (IC50 = 97 nM), was studied in a mouse model of bleomycin-induced pulmonary fibrosis [31]. This evidence concerns the gene HDAC6 and pulmonary fibrosis.