The adjusted regression analysis model for tumor protein expression comparing BMI-based groups showed that the class I/II obesity (vs. normal/overweight) group was significantly associated with higher expression of fibronectin (log2-fold change = 0.7, p-value = 0.034), Tumor Protein P53 Binding Protein 1 (TP53BP1; log2-fold change = 0.7, p-value = 0.043), and Carbonic Anhydrase 9 (CA9; log2-fold change = 0.9, p-value = 0.043) but lower expression of phospho-S6 (S240/S244) (log2-fold change = −0.7, p-value = 0.038) (Supplemental Table S5 and Supplemental Figure S4A). Here, FN1 is linked to obesity due to melanocortin 4 receptor deficiency.