Notably, EGR1 appeared as the top-ranking candidate MR-IE in multiple cancer types, such as GBM, DLBC, ESCA, LUAD, LUSC, MESO, ACC, STAD, COAD-READ, BLCA, PAAD, OV, UCEC, and CESC, Whereas MYC appears to be the top-ranking candidate particularly for liver and renal associated cancers (i.e., LIHC, CHOL, KICH, KIPAN, KIRC, and KIRP). Here, MYC is linked to cancer.