BRD4 and nut midline carcinoma: When dysregulated, BRD4 can play a role in upregulating oncogenes and disrupting the cell cycle, as seen in nuclear protein in testis (NUT) midline carcinoma (NMC), where a BRD4-NUT fusion recruits histone acetyl transferases, subsequently promoting MYC upregulation and inhibiting cell differentiation [186,187].