As shown in Figure 5B and Table S1, mouse chemokines CCL21 (~224-fold), CXCL13 (~66-fold), CCL6 (~17-fold), CCL11 (~18-fold), CCL8 (~3-fold), CCL12 (~4-fold), CCL9/10 (~9-fold), CCL5 (~32-fold), and CXCL12 (~6-fold) were significantly upregulated in MDA-PCa-2b-CXCR1, as compared to MDA-PCa-2b-CXCR2 and MDA-PCa-2b-Vec tumors. This evidence concerns the gene CXCL12 and posterior cortical atrophy.