In this study, we investigated the role of CXCR1 expression in prostate tumor, using the androgen-dependent cell line MDA-PCa-2b to stably express CXCR1 (MDA-PCa-2b-CXCR1) and, for control, cells expressing CXCR2 (MDA-PCa-2b-CXCR2) or vector alone (MDA-PCa-2b-vec). Here, CXCR2 is linked to prostate neoplasm.