Similarly, Liu et al. reported that 6-gingerol, a functional component of Z. officinale, reduces the transcription of fibrosis-related factors such as α-SMA in lung fibroblasts treated with TGF-β1 and has shown effectiveness in reducing inflammation and fibrosis in a bleomycin-induced pulmonary fibrosis mouse model [69]. Here, ACTA1 is linked to pulmonary fibrosis.