PRDX4 and type 2 diabetes mellitus: Additionally, the pooled serum levels of PRX1 (SMD: 0.90, 95% CI: 0.55–1.25, p < 0.001), PRX2 (SMD: 1.21, 95% CI: 0.85–1.57, p < 0.001), PRX4 (SMD: 0.49, 95% CI: 0.26–0.73, p < 0.001), and PRX6 (SMD: 0.65, 95% CI: 0.31–1.00, p < 0.001) were significantly higher in patients with T2D than in controls (Figure 2).