Additionally, a recent study revealed a novel SDHD mutation (c.298-301delACTC) that results in premature termination of the protein at position 133 [42], establishing, for the first time, a link between SDHD gene mutations and hereditary pheochromocytoma/paraganglioma as well as GH-secreting pituitary adenomas. Here, SDHD is linked to hereditary pheochromocytoma-paraganglioma.