CSF3 and Thrombocytopenia: Since in normal haematopoiesis, the platelets are produced from megakaryocytes, ref. [54] also analysed the number of cells in the bone marrow and spleen, respectively, in mice treated with G-CSF, concluding that a spontaneous improvement of G-CSF induced thrombocytopenia is not related to the number of megakaryocytes in the bone marrow.