The expression of hub genes RRM2, MELK, KIF11, KIF23, NCAPG, DLGAP5, BUB1B, AURKB, CCNB1, KIF20A, CCNA2, TTK, PBK, TOP2A, CDK1, MAD2L1, BIRC5, ASPM, CDCA8, and CENPF was validated using GEPIA in HCC. The gene discussed is NCAPG; the disease is hepatocellular carcinoma.