Ten hub genes, AURKA, CDC20, FTCD, UBE2C, CCNB2, PTTG1, CDKN3, CKS1B, TOP2A, and KIF20A, were identified as the key genes in HCC that to be significantly correlated with the survival of patients with HCC [63]. This evidence concerns the gene PTTG1 and hepatocellular carcinoma.