The top 20 most strongly enriched KEGG pathways are presented in Figure 6 and included the pathways in cancer, proteoglycans in cancer, lipid and atherosclerosis, endocrine resistance, EGFR tyrosine kinase inhibitor resistance, PI3K/Akt signaling, prostate cancer, estrogen signaling, Ras signaling, and MAPK signaling pathways. The gene discussed is AKT1; the disease is atherosclerosis.