Group A: 1 case of schizophrenia, 1 case of blunt trauma history, 1 case of syphilis, 1 case of hepatitis B carrier, 3 cases of abnormal thyroid function detection (at least one index of FT3, FT4, TSH, A-TG, TG, A-TPO is abnormal, a total of 10 cases of examination records); In group B, thyroid function was abnormal in 1 case (9 cases were recorded), and hepatitis B was carried in 1 case. This evidence concerns the gene TPO and syphilis.