MDM2 and glioblastoma: An in vitro anticancer analysis using the human glioblastoma cell line model (U87MG) demonstrated that carnosol, a phenolic diterpene found in rosemary, regulated cellular proliferation by increasing intracellular p53 levels, promoting its transcriptional reactivation, degrading the p53-MDM2 interaction, and inducing apoptosis and cell cycle arrest.