TP53 and cancer: 3) (References in Table 3: Chen et al., 2022[32]; Giacomelli et al., 2016[62]; Li et al., 2021[121]; Luo et al., 2020[127]; Rahman et al., 2024[177]) summarizes studies demonstrating the synergistic effects of natural products on the p53-MDM2 interaction in various experimental cancer models.